×
Pour une meilleure utilisation, nous vous conseillons d’activer Javascript dans votre navigateur.
Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide
CDKN1C
Reactivité: Humain
Hôte: Synthetic
WB
N° du produit ABIN5518457
Détail du produit
(cache)
Antigène
Tous les produits CDKN1C
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Protein Region
Middle Region
Origine
Humain
Source
Toutes les hôtes sur CDKN1C Peptides
Synthetic
Application
Western Blotting (WB)
Séquence
SACRSLFGPV DHEELSRELQ ARLAELNAED QNRWDYDFQQ DMPLRGPGRL
Alternatives
(show)
Information d'application
(cache)
Restrictions
For Research Use only
Stockage
(cache)
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Détail du antigène
(cache)
Antigène
CDKN1C
(Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
Synonymes
BWCR Peptide, BWS Peptide, KIP2 Peptide, WBS Peptide, p57 Peptide, p57Kip2 Peptide, cb961 Peptide, p27Xic1-a Peptide, zgc:86618 Peptide, AL024410 Peptide, CDKI Peptide, Kip2 Peptide, p57(kip2) Peptide, p57KIP2 Peptide, cyclin dependent kinase inhibitor 1C Peptide, cyclin-dependent kinase inhibitor 1Ca Peptide, cyclin-dependent kinase inhibitor 1C (P57) Peptide, cyclin-dependent kinase inhibitor 1C Peptide, CDKN1C Peptide, cdkn1ca Peptide, Cdkn1c Peptide
Sujet
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2, Protein Size: 316
ID gène
1028
NCBI Accession
NM_000076 , NP_000067
UniProt
P49918
Vus récemment
(cache)