Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide
Aperçu rapide pour Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C) (Middle Region) Peptide (ABIN5518457)
Antigène
Origine
Source
Application
-
-
Protein Region
- Middle Region
-
Séquence
- SACRSLFGPV DHEELSRELQ ARLAELNAED QNRWDYDFQQ DMPLRGPGRL
-
-
-
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))
-
Sujet
-
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BWS, WBS, p57, BWCR, KIP2, p57Kip2,
Protein Size: 316 -
ID gène
- 1028
-
NCBI Accession
- NM_000076, NP_000067
-
UniProt
- P49918
Antigène
-