Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide
CIDEA
Reactivité: Humain
Hôte: Synthetic
WB
N° du produit ABIN5518475
Aperçu rapide pour Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide (ABIN5518475)
Antigène
CIDEA
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
Origine
Humain
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- RPFRVSNHDR SSRRGVMASS LQELISKTLD ALVIATGLVT LVLEEDGTVV
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
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Sujet
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This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Alias Symbols: CIDE-A,
Protein Size: 219 -
ID gène
- 1149
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NCBI Accession
- NM_001279, NP_001270
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UniProt
- O60543
Antigène
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