Hemoglobin A-2 Peptide
Aperçu rapide pour Hemoglobin A-2 Peptide (ABIN5624564)
Antigène
Source
Application
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Type de proteíne
- Synthetic
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N° du produit (Fournisseur)
- 000-001-gs8
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Fournisseur
- Rockland
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Fonction
- HbA-2 Control Peptide
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Attributs du produit
- HbA-2 Control Peptide, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, Sickle Cell Disease (SCD)
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Purification
- Greater than 95% specific peptide
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Pureté
- Greater than 95% specific peptide
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Indications d'application
- Optional[Flow Cytometry Dilution]: HbA-2 peptide can be used as a control with the HbA-2 antibody. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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Concentration
- 1.0 mg/mL
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Buffer
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Buffer: None
Stabilizer: None
Preservative: None -
Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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Date de péremption
- 6 months
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- Hemoglobin A-2
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Sujet
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Synonyms: HbA-2 Control Peptide, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, Sickle Cell Disease (SCD)
Background: HbA-2 or HbD peptide corresponds the delta-subunit specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (α2β2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1 % of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbD peptide is suitable for use as a control with HbA-2 antibody. This peptide is ideal for investigators involved in Cardiovascular and developmental biology research.
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ID gène
- 3045
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NCBI Accession
- NP_000510
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UniProt
- P02042
Antigène
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