V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Peptide
Aperçu rapide pour V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Peptide (ABIN5624574)
Antigène
Source
Application
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Type de proteíne
- Synthetic
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N° du produit (Fournisseur)
- 000-001-j35
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Fournisseur
- Rockland
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Fonction
- AKT2 Control Peptide
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Attributs du produit
- AKT 2, AKT-2, PKB, PKB beta, PKBBETA PRKBB, Protein kinase Akt 2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, blocking peptide
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Purification
- Purity was determined to be greater than 98% by analysis by RP-HPLC and by reducing and non-reducing SDS-PAGE.
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Pureté
- Greater than 98% by analysis by RP-HPLC and by reducing and non-reducing SDS-PAGE.
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V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) peptide
AKT2 Hôte: Synthetic WB, CP Sodium azide
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Indications d'application
- Optional[Flow Cytometry Dilution]: AKT2 Control peptide has been tested by western blot and is suitable as a control for polyclonal or monoclonal Anti-AKT2 in immunological assays.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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Concentration
- 1.0 mg/mL
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Buffer
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Buffer: None
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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Date de péremption
- 6 months
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- AKT2 (V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2))
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Sujet
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Synonyms: AKT 2, AKT-2, PKB, PKB beta, PKBBETA PRKBB, Protein kinase Akt 2, Protein kinase B beta, RAC-beta serine/threonine-protein kinase, RAC-PK-beta, blocking peptide
Background: AKT2 peptide detects AKT2 which is a component of the PI-3 kinase pathway and is activated by phosphorylation at Ser 473 and Thr 308. AKT is a cytoplasmic protein also known as Protein Kinase B (PKB) and rac (related to A and C kinases). AKT is a key regulator of many signal transduction pathways. AKT Exhibits tight control over cell proliferation and cell viability. Overexpression or inappropriate activation of AKT is noted in many types of cancer. AKT mediates many of the downstream events of PI 3-kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI 3-kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus. AKT has two main roles: (i) inhibition of apoptosis, (ii) promotion of proliferation.
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ID gène
- 208
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UniProt
- P31751
Antigène
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