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Forkhead Box P2 (FOXP2) (N-Term) Peptide

FOXP2 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5671584

Aperçu rapide pour Forkhead Box P2 (FOXP2) (N-Term) Peptide (ABIN5671584)

Antigène

FOXP2 (Forkhead Box P2 (FOXP2))

Origine

Humain

Source

  • 6
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    MQESATETIS NSSMNQNGMS TLSSQLDAGS RDGRSSGDTS SEVSTVELLH

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti- FOXP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    FOXP2 (Forkhead Box P2 (FOXP2))

    Sujet

    This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

    Alias Symbols: SPCH1, CAGH44, TNRC10

    Protein Size: 432

    ID gène

    93986

    NCBI Accession

    NM_001172766, NP_001166237
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