Translin (TSN) (Middle Region) Peptide
TSN
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits Translin (TSN)
- Translin (TSN)
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- SRLSVNSVTA GDYSRPLHIS TFINELDSGF RLLNLKNDSL RKRYDGLKYD
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- TSN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Translin (TSN)
- Synonymes
- tsn Peptide, MGC52533 Peptide, TSN Peptide, CG11761 Peptide, Dmel\\CG11761 Peptide, TB-RBP Peptide, BCLF-1 Peptide, C3PO Peptide, RCHF1 Peptide, REHF-1 Peptide, TBRBP Peptide, TRSLN Peptide, 2610034C24Rik Peptide, AU040286 Peptide, translin L homeolog Peptide, translin Peptide, haloacid dehalogenase Peptide, Translin Peptide, tsn.L Peptide, TSN Peptide, trsn Peptide, MMAH_RS03470 Peptide, TAGG_RS05275 Peptide, Igag_0962 Peptide, MFER_RS03645 Peptide, DESMU_RS01315 Peptide, ARCVE_RS05265 Peptide, MZHIL_RS01310 Peptide, Tsn Peptide
- Sujet
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This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants.
Alias Symbols: C3PO, RCHF1, TBRBP, TRSLN, BCLF-1, REHF-1
Protein Size: 228 - ID gène
- 7247
- NCBI Accession
- NM_001261401, NP_001248330
- UniProt
- Q15631
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