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Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptide

EIF2C1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5672141
150,78 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 15 à 22 jours ouvrables

Aperçu rapide pour Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1) (C-Term) Peptide (ABIN5672141)

Antigène

AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

Origine

Humain

Source

  • 4
  • 1
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Séquence

    RSVSIPAPAY YARLVAFRAR YHLVDKEHDS GEGSHISGQS NGRDPQALAK

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti- EIF2C1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    AGO1 (EIF2C1) (Eukaryotic Translation Initiation Factor 2C, 1 (EIF2C1))

    Sujet

    This gene encodes a member of the argonaute family of proteins, which associate with small RNAs and have important roles in RNA interference (RNAi) and RNA silencing. This protein binds to microRNAs (miRNAs) or small interfering RNAs (siRNAs) and represses translation of mRNAs that are complementary to them. It is also involved in transcriptional gene silencing (TGS) of promoter regions that are complementary to bound short antigene RNAs (agRNAs), as well as in the degradation of miRNA-bound mRNA targets. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A recent study showed this gene to be an authentic stop codon readthrough target, and that its mRNA could give rise to an additional C-terminally extended isoform by use of an alternative in-frame translation termination codon.

    Alias Symbols: Q99, EIF2C, hAgo1, EIF2C1, GERP95

    Protein Size: 857

    ID gène

    26523

    NCBI Accession

    NM_012199, NP_036331

    UniProt

    Q9UL18
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