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Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide

ACCN3 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5672368

Aperçu rapide pour Amiloride-Sensitive Cation Channel 3 (ACCN3) (N-Term) Peptide (ABIN5672368)

Antigène

ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Origine

Humain

Source

  • 5
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Séquence

    MKPTSGPEEA RRPASDIRVF ASNCSMHGLG HVFGPGSLSL RRGMWAAAVV

    Attributs du produit

    This is a synthetic peptide designed for use in combination with anti- ACCN3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène

    ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

    Sujet

    This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium. Alternatively spliced transcript variants have been described.

    Alias Symbols: ACCN3, TNaC1, DRASIC, SLNAC1

    Protein Size: 531

    ID gène

    9311

    NCBI Accession

    NM_004769, NP_004760

    UniProt

    Q9UHC3
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