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Deleted in Azoospermia-Like (DAZL) (Middle Region) Peptide

DAZL Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5672476
  • Antigène Tous les produits DAZL
    DAZL (Deleted in Azoospermia-Like (DAZL))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    EATPPSGNGP QKKSVDRSIQ TVVSCLFNPE NRLRNSVVTQ DDYFKDKRVH
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti- DAZL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    DAZL (Deleted in Azoospermia-Like (DAZL))
    Synonymes
    DAZH Peptide, DAZL1 Peptide, DAZLA Peptide, SPGYLA Peptide, DAZL Peptide, Xdazl Peptide, dazh Peptide, dazl1 Peptide, dazla Peptide, spgyla Peptide, dazl-B Peptide, dazl-a Peptide, Daz-like Peptide, Dazh Peptide, Dazl1 Peptide, Dazla Peptide, Tpx-2 Peptide, Tpx2 Peptide, deleted in azoospermia like Peptide, deleted in azoospermia-like Peptide, deleted in azoospermia-like L homeolog Peptide, DAZL Peptide, dazl Peptide, Dazl Peptide, dazl.L Peptide
    Sujet
    The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: DAZH, DAZL1, DAZLA, SPGYLA

    Protein Size: 295
    ID gène
    1618
    NCBI Accession
    NM_001190811, NP_001177740
    UniProt
    Q92904
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