PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide
PINX1
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN5673446
Aperçu rapide pour PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide (ABIN5673446)
Antigène
PINX1
(PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Séquence
- LGLGATINNE DNWIAHQDDF NQLLAELNTC HGQETTDSSD KKEKKSFSLE
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Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- PINX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) peptide
PINX1 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
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Sujet
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Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors. May be required for the survival of both hematopoietic and endothelial precursors during specification. Competes with GATA4 for binding and activation of the FGF3 promoter. Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.
Alias Symbols: Gno1, LPTL, LPTS, Pxr1
Protein Size: 440 -
ID gène
- 54984
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NCBI Accession
- NM_001284356, NP_001271285
Antigène
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