This is a synthetic peptide designed for use in combination with anti- RAD51L1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
RAD51 Homolog B (Rad51B)
Synonymes
R51H2 Peptide, RAD51L1 Peptide, REC2 Peptide, AI553500 Peptide, Rad51l1 Peptide, mREC2 Peptide, ATRAD51B Peptide, T17D12.12 Peptide, T17D12_12 Peptide, RGD1560681 Peptide, rad51l1 Peptide, wu:fd07f04 Peptide, zgc:56581 Peptide, RAD51 paralog B Peptide, DNA repair (Rad51) family protein Peptide, Rad51 DNA recombinase 2 Peptide, RAD51B Peptide, Rad51b Peptide, rad51b Peptide
Sujet
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.