2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) Peptide
Aperçu rapide pour 2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) Peptide (ABIN8093608)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- OAS1 Peptide - C-terminal region
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Séquence
- AESNSADDET DDPRRYQKYG YIGTHEYPHF SHRPSTLQAA STPQAEEDWT
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-OAS1 Antibody (ARP72600_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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Sujet
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Background Information: This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.
Alternative Symbols: OAS1, OIAS,
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Poids moléculaire
- 44kDa
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ID gène
- 4938
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NCBI Accession
- NP_058132
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UniProt
- P00973
Antigène
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