BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide
Aperçu rapide pour BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide (ABIN8095547)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- BID Peptide - C-terminal region
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Séquence
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
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BH3 Interacting Domain Death Agonist (BID) peptide
BID Reactivité: Humain Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-BID Antibody (ARP61037_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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Sujet
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Background Information: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alternative Symbols: FP497, MGC15319, MGC42355
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Poids moléculaire
- 27kDa
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ID gène
- 637
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NCBI Accession
- NP_932070
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UniProt
- B3KT21
Antigène
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