COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) Peptide
Aperçu rapide pour COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2) Peptide (ABIN8097918)
Antigène
Source
Application
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Fonction
- COPS2 Peptide
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-COPS2 antibody ( ARP34189_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- COPS2 (COP9 Constitutive Photomorphogenic Homolog Subunit 2 (Arabidopsis) (COPS2))
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Sujet
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Targeted Subunit: 2
Background Information: COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Alternative Symbols: ALIEN, CSN2, SGN2, TRIP15
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Poids moléculaire
- 52kDa
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ID gène
- 9318
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NCBI Accession
- NP_004227
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UniProt
- P61201
Antigène
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