Death-Domain Associated Protein (DAXX) (C-Term) Peptide
DAXX
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN8098692
168,15 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 6 à 9 jours ouvrables
Aperçu rapide pour Death-Domain Associated Protein (DAXX) (C-Term) Peptide (ABIN8098692)
Antigène
DAXX
(Death-Domain Associated Protein (DAXX))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Fonction
- DAXX Peptide - C-terminal region
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Séquence
- VSSTSFNGGV SPHNWGDSGP PCKKSRKEKK QTGSGPLGNS YVERQRSVHE
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-DAXX Antibody (ARP60158_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- DAXX (Death-Domain Associated Protein (DAXX))
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Sujet
- This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination.
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Poids moléculaire
- 78kDa
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ID gène
- 1616
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UniProt
- Q9UER7
Antigène
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