Glucosidase, Alpha, Acid (GAA) Peptide
Aperçu rapide pour Glucosidase, Alpha, Acid (GAA) Peptide (ABIN8101556)
Antigène
Source
Application
-
-
Fonction
- GAA Peptide
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
This is a synthetic peptide designed for use in combination with anti-GAA antibody ( ARP44226_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- GAA (Glucosidase, Alpha, Acid (GAA))
-
Sujet
-
Background Information: GAA is acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. This gene encodes acid alpha-glucosidase, which is essential for the degradation of glycogen to glucose in lysosomes. Different forms of acid alpha-glucosidase are obtained by proteolytic processing. Defects in this gene are the cause of glycogen storage disease II, also known as Pompe's disease, which is an autosomal recessive disorder with a broad clinical spectrum. Three transcript variants encoding the same protein have been found for this gene.
Alternative Symbols: LYAG
-
Poids moléculaire
- 98kDa
-
ID gène
- 2548
-
NCBI Accession
- NP_000143
-
UniProt
- P10253
Antigène
-
