Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide
Aperçu rapide pour Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) (Middle Region) Peptide (ABIN8101591)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Fonction
- GRIA4 Peptide - middle region
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Séquence
- RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL
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Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4) peptide
GRIA4 Reactivité: Humain, Souris, Rat, Boeuf (Vache) Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-GRIA4 Antibody (ARP76224_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))
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Sujet
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Background Information: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA, R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia.
Alternative Symbols: GRIA4,GLUR4,
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Poids moléculaire
- 47kDa
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ID gène
- 2893
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UniProt
- P48058
Antigène
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