Hemoglobin, gamma G (HBG2) (C-Term) Peptide
Aperçu rapide pour Hemoglobin, gamma G (HBG2) (C-Term) Peptide (ABIN8102343)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- HBG2 Peptide - C-terminal region
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Séquence
- KLHVDPENFK LLGNVLVTVL AIHFGKEFTP EVQASWQKMV TGVASALSSR
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- HBG2 (Hemoglobin, gamma G (HBG2))
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Sujet
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Background Information: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
Alternative Symbols: TNCY, HBG-T1,
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Poids moléculaire
- 16 kDa
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ID gène
- 3048
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NCBI Accession
- NP_000175
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UniProt
- P69892
Antigène
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