Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptide
Aperçu rapide pour Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (C-Term) Peptide (ABIN8104388)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- LAIR1 Peptide - C-terminal region
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Séquence
- HRQNQIKQGP PRSKDEEQKP QQRPDLAVDV LERTADKATV NGLPEKDRET
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Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1) (AA 22-125), (Extracellular Domain) peptide
LAIR1 Reactivité: Humain Hôte: Escherichia coli (E. coli) SDS
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-LAIR1 Antibody (ARP74615_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LAIR1 (Leukocyte-Associated Immunoglobulin-Like Receptor 1 (LAIR1))
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Sujet
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Background Information: The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including natural killer cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily. The encoded protein has been identified as an anchor for tyrosine phosphatase SHP-1, and may induce cell death in myeloid leukemias. Alternative splicing results in multiple transcript variants.
Alternative Symbols: LAIR1,CD305,
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Poids moléculaire
- 31kDa
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ID gène
- 3903
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UniProt
- Q6GTX8
Antigène
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