Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide
Aperçu rapide pour Lymphocyte-Specific Protein tyrosine Kinase (LCK) (N-Term) Peptide (ABIN8104635)
Antigène
Origine
Source
Application
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Protein Region
- N-Term
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Fonction
- LCK Peptide - N-terminal region
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Séquence
- ENCHYPIVPL DGKGTLLIRN GSEVRDPLVT YEGSNPPASP LQDNLVIALH
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-LCK Antibody (ARP54524_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- LCK (Lymphocyte-Specific Protein tyrosine Kinase (LCK))
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Sujet
- LCK is a member of the Src family of protein tyrosine kinases (PTKs). It is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. LCK localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules.
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Poids moléculaire
- 39kDa
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ID gène
- 3932
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UniProt
- P06239
Antigène
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