Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) Peptide
Aperçu rapide pour Methyl-CpG Binding Domain Protein 1 (MBD1) (C-Term) Peptide (ABIN8105268)
Antigène
Origine
Source
Application
-
-
Protein Region
- C-Term
-
Fonction
- MBD1 Peptide - C-terminal region
-
Séquence
- EEDKEENKDD SASKLAPEEE AGGAGTPVIT EIFSLGGTRF RDTAVWLPRS
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
This is a synthetic peptide designed for use in combination with anti-MBD1 Antibody (ARP32693_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- MBD1 (Methyl-CpG Binding Domain Protein 1 (MBD1))
-
Sujet
-
Background Information: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions, several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides, transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alternative Symbols: CXXC3, PCM1, RFT
-
Poids moléculaire
- 69kDa
-
ID gène
- 4152
-
NCBI Accession
- NP_001191067
-
UniProt
- Q9UIS9
Antigène
-
