Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
Aperçu rapide pour Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN8109720)
Antigène
Source
Application
-
-
Fonction
- PYHIN1 Peptide
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody ( ARP50876_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
-
Sujet
-
Background Information: PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alternative Symbols: IFIX, MGC23885, RP11-520H16.1
-
Poids moléculaire
- 51kDa
-
ID gène
- 149628
-
NCBI Accession
- NP_945148
-
UniProt
- Q6K0P9
Antigène
-
