RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptide
Aperçu rapide pour RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptide (ABIN8110078)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- RASAL1 Peptide - C-terminal region
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Séquence
- DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
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RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) peptide
RASAL1 Reactivité: Humain Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-RASAL1 Antibody (ARP62227_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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Sujet
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Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Alternative Symbols: RASAL
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Poids moléculaire
- 88kDa
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ID gène
- 8437
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NCBI Accession
- NP_004649
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UniProt
- O95294
Antigène
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