Regulatory Factor X 5 (RFX5) Peptide
RFX5
Hôte: Synthetic
BP, WB
N° du produit ABIN8110250
168,15 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 6 à 9 jours ouvrables
Aperçu rapide pour Regulatory Factor X 5 (RFX5) Peptide (ABIN8110250)
Antigène
RFX5
(Regulatory Factor X 5 (RFX5))
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Fonction
- RFX5 Peptide
-
-
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
This is a synthetic peptide designed for use in combination with anti-RFX5 antibody ( ARP37992_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Stock
- -20 °C
-
Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- RFX5 (Regulatory Factor X 5 (RFX5))
-
Sujet
- RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. RFX is a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX.A lack of MHC-II expression results in a severe immunodeficiency syndrome called MHC-II deficiency, or the bare lymphocyte syndrome (BLS, MIM 209920). At least 4 complementation groups have been identified in B-cell lines established from patients with BLS. The molecular defects in complementation groups B, C, and D all lead to a deficiency in RFX, a nuclear protein complex that binds to the X box of MHC-II promoters. The lack of RFX binding activity in complementation group C results from mutations in the RFX5 gene encoding the 75-kD subunit of RFX (Steimle et al., 1995). RFX5 is the fifth member of the growing family of DNA-binding proteins sharing a novel and highly characteristic DNA-binding domain called the RFX motif. Multiple alternatively spliced transcript variants have been found but the full-length natures of only two have been determined.
-
Poids moléculaire
- 68kDa
-
ID gène
- 5993
-
NCBI Accession
- NP_001020774
-
UniProt
- P48382
Antigène
-
Vous êtes ici:
