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Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide

RRM2B Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN8110591
168,15 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 6 à 9 jours ouvrables

Aperçu rapide pour Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide (ABIN8110591)

Antigène

RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

Origine

Humain

Source

  • 4
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    Middle Region

    Fonction

    RRM2B Peptide - middle region

    Séquence

    VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
  • Indications d'application

    Optimal working dilution should be determined by the investigator.

    Commentaires

    This is a synthetic peptide designed for use in combination with anti-RRM2B Antibody (ARP46032_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Buffer

    Lyophilized powder

    Stock

    -20 °C

    Stockage commentaire

    For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
  • Antigène

    RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))

    Sujet

    This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.

    Poids moléculaire

    32kDa

    ID gène

    50484

    UniProt

    Q7LG56
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