Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide
Aperçu rapide pour Transducin (Beta)-Like 1X-Linked (TBL1X) (Middle Region) Peptide (ABIN8114220)
Antigène
Origine
Source
Application
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Protein Region
- Middle Region
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Fonction
- TBL1X Peptide - middle region
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Séquence
- HNKEIYTIKW SPTGPATSNP NSNIMLASAS FDSTVRLWDI ERGVCTHTLT
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- TBL1X (Transducin (Beta)-Like 1X-Linked (TBL1X))
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Sujet
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Background Information: The protein encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. Four transcript variants encoding two different isoforms have been found for this gene. This gene is highly similar to the Y chromosome TBL1Y gene.
Alternative Symbols: EBI, TBL1, SMAP55
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Poids moléculaire
- 62 kDa
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ID gène
- 6907
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NCBI Accession
- NP_001132938
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UniProt
- O60907
Antigène
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