Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (C-Term) Peptide
Aperçu rapide pour Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1) (C-Term) Peptide (ABIN8115247)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- UBE2V1 Peptide - C-terminal region
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Séquence
- GVVDPRAISV LAKWQNSYSI KVVLQELRRL MMSKENMKLP QPPEGQCYSN
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-UBE2V1 Antibody (ARP61716_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UBE2V1 (Ubiquitin-Conjugating Enzyme E2 Variant 1 (UBE2V1))
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Sujet
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Background Information: Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene is located in the nucleus and can cause transcriptional activation of the human FOS proto-oncogene. It is thought to be involved in the control of differentiation by altering cell cycle behavior. Multiple alternatively spliced transcripts encoding different isoforms have been described for this gene. A pseudogene has been identified which is also located on chromosome 20. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (Kua-UEV), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.
Alternative Symbols: CIR1, CROC-1, CROC1, UBE2V, UEV-1, UEV1, UEV1A
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Poids moléculaire
- 16kDa
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ID gène
- 7335
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NCBI Accession
- NP_001027459
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UniProt
- Q13404
Antigène
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