Unc-13 Homolog B (UNC13B) (Middle Region) Peptide
UNC13B
Reactivité: Humain
Hôte: Synthetic
BP, WB
N° du produit ABIN8115449
168,15 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination:
France
Envoi sous 6 à 9 jours ouvrables
Aperçu rapide pour Unc-13 Homolog B (UNC13B) (Middle Region) Peptide (ABIN8115449)
Antigène
UNC13B
(Unc-13 Homolog B (UNC13B))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Fonction
- UNC13B Peptide - middle region
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Séquence
- SYDLDYPERR AISPTSSSRY GSSCNVSQGS SQLSELDQYH EQDDDHRETD
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNC13B (Unc-13 Homolog B (UNC13B))
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Sujet
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Background Information: This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis.
Alternative Symbols: UNC13, MUNC13, Unc13h2
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Poids moléculaire
- 181 kDa
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ID gène
- 10497
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NCBI Accession
- NP_006368
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UniProt
- O14795
Antigène
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