Unc-13 Homolog D (UNC13D) (C-Term) Peptide
Aperçu rapide pour Unc-13 Homolog D (UNC13D) (C-Term) Peptide (ABIN8115450)
Antigène
Origine
Source
Application
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Protein Region
- C-Term
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Fonction
- UNC13D Peptide - C-terminal region
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Séquence
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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This is a synthetic peptide designed for use in combination with anti-UNC13D Antibody (ARP64215_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Stock
- -20 °C
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Stockage commentaire
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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Sujet
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Background Information: This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alternative Symbols: FHL3, HLH3, HPLH3, Munc13-4
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Poids moléculaire
- 119kDa
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ID gène
- 201294
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NCBI Accession
- NP_954712
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UniProt
- Q70J99
Antigène
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