A synthetic peptide for use as a blocking control in assays to test for specificity of SELE antibody, Alternative Names: SELE control peptide, SELE antibody Blocking Peptide, Anti-SELE Blocking Peptide, selectin E Blocking Peptide, CD62E Blocking Peptide, ELAM Blocking Peptide, ELAM1 Blocking Peptide, ESEL Blocking Peptide, LECAM2 Blocking Peptide
The protein encoded by this gene is found in cytokine-stimulated endothelial cells and is thought to be responsible for the accumulation of blood leukocytes at sites of inflammation by mediating the adhesion of cells to the vascular lining. It exhibits structural features such as the presence of lectin- and EGF-like domains followed by short consensus repeat (SCR) domains that contain 6 conserved cysteine residues. These proteins are part of the selectin family of cell adhesion molecules. Adhesion molecules participate in the interaction between leukocytes and the endothelium and appear to be involved in the pathogenesis of atherosclerosis.