Minichromosome Maintenance Complex Component 3 (MCM3) Peptide
MCM3
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936013
Aperçu rapide pour Minichromosome Maintenance Complex Component 3 (MCM3) Peptide (ABIN936013)
Antigène
MCM3
(Minichromosome Maintenance Complex Component 3 (MCM3))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- YAYFKKVLEK EKKRKKRSED ESETEDEEEK SQEDQEQKRK RRKTRQPDAK
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of MCM3 antibody,
Alternative Names: MCM3 control peptide, MCM3 antibody Blocking Peptide, Anti-MCM3 Blocking Peptide, Minichromosome Maintenance Complex Component 3 Blocking Peptide, HCC5 Blocking Peptide, MGC1157 Blocking Peptide, P1-MCM3 Blocking Peptide, P1.h Blocking Peptide, RLFB Blocking Peptide, MCM3, MCM-3, MCM 3, MCM-3 Blocking Peptide, MCM 3 Blocking Peptide -
Purification
- The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))
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Sujet
- MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.
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Poids moléculaire
- 91 kDa
Antigène
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