Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptide
PARK2
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936245
Aperçu rapide pour Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2) Peptide (ABIN936245)
Antigène
Parkin (PARK2)
(Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- YTRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEQGQRKVT CEGGNGLGCG
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of Park2 antibody,
Alternative Names: Park2 control peptide, Park2 antibody Blocking Peptide, Anti-Park2 Blocking Peptide, Parkinson disease, autosomal recessive, juvenile 2, parkin Blocking Peptide, MGC130518 Blocking Peptide, PRKN Blocking Peptide, Park2, Park-2, Park 2, Park-2 Blocking Peptide, Park 2 Blocking Peptide -
Purification
- Serum
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))
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Sujet
- Park2 functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include SYT11, CCNE1, GPR37, STUB1, a 22 kDa O-linked glycosylated isoform of SNCAIP, SEPT5 and AIMP2. Park2 may play a more general role in the ubiquitin proteasomal pathway by participating in the removal and/or detoxification of abnormally folded or damaged protein. Park2 limits the production of reactive oxygen species (ROS).
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Poids moléculaire
- 51 kDa
Antigène
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