A synthetic peptide for use as a blocking control in assays to test for specificity of EPB49 antibody, Alternative Names: EPB49 control peptide, EPB49 antibody Blocking Peptide, Anti-EPB49 Blocking Peptide, erythrocyte membrane protein band 4.9, dematin Blocking Peptide, DMT Blocking Peptide, FLJ78462 Blocking Peptide, FLJ98848 Blocking Peptide, EPB49, EPB-49, EPB 49, EPB-49 Blocking Peptide, EPB 49 Blocking Peptide
Purification
Prepared from sheep serum by affinity purification using an AminoLink® Plus column matrix to which purified, recombinant bovine DDC was coupled.
Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.