Galanin Receptor 2 (GALR2) Peptide
GALR2
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936382
Aperçu rapide pour Galanin Receptor 2 (GALR2) Peptide (ABIN936382)
Antigène
GALR2
(Galanin Receptor 2 (GALR2))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of GALR2 antibody,
Alternative Names: GALR2 control peptide, GALR2 antibody Blocking Peptide, Anti-GALR2 Blocking Peptide, galanin receptor 2 Blocking Peptide, GALNR2 Blocking Peptide, MGC125983 Blocking Peptide, MGC125984 Blocking Peptide, GALR2, GALR-2, GALR 2, GALR-2 Blocking Peptide, GALR 2 Blocking Peptide
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Galanin Receptor 2 (GALR2) peptide
GALR2 Reactivité: Humain, Boeuf (Vache), Souris, Chien, Rat Hôte: Synthetic BP, Imm
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- GALR2 (Galanin Receptor 2 (GALR2))
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Sujet
- Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
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Poids moléculaire
- 43 kDa
Antigène
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