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Galanin Receptor 2 (GALR2) Peptide

GALR2 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN936382
  • Antigène Tous les produits GALR2
    GALR2 (Galanin Receptor 2 (GALR2))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of GALR2 antibody,
    Alternative Names: GALR2 control peptide, GALR2 antibody Blocking Peptide, Anti-GALR2 Blocking Peptide, galanin receptor 2 Blocking Peptide, GALNR2 Blocking Peptide, MGC125983 Blocking Peptide, MGC125984 Blocking Peptide, GALR2, GALR-2, GALR 2, GALR-2 Blocking Peptide, GALR 2 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    GALR2 (Galanin Receptor 2 (GALR2))
    Synonymes
    GALNR2 Peptide, mGalR Peptide, GALR2 Peptide, GAL2-R Peptide, GALR-2 Peptide, galanin receptor 2 Peptide, transcription regulator. LacI family, raffinose related Peptide, DNA-binding transcriptional regulator GalR Peptide, galactose operon repressor Peptide, galanin receptor type 2 Peptide, GALR2 Peptide, Galr2 Peptide, LOC100037698 Peptide, rafR Peptide, galR2 Peptide, LOC103690156 Peptide
    Sujet
    Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
    Poids moléculaire
    43 kDa
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