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Glucokinase (Hexokinase 4) (GCK) Peptide

GCK Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN936387
  • Antigène Tous les produits GCK
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RVMLVKVGEG EEGQWSVKTK HQMYSIPEDA MTGTAEMLFD YISECISDFL
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of GCK antibody,
    Alternative Names: GCK control peptide, GCK antibody Blocking Peptide, Anti-GCK Blocking Peptide, glucokinase, hexokinase 4 Blocking Peptide, FGQTL3 Blocking Peptide, GK Blocking Peptide, GLK Blocking Peptide, HHF3 Blocking Peptide, HK4 Blocking Peptide, HKIV Blocking Peptide, HXKP Blocking Peptide, MODY2 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    GCK (Glucokinase (Hexokinase 4) (GCK))
    Synonymes
    FGQTL3 Peptide, GK Peptide, GLK Peptide, HHF3 Peptide, HK4 Peptide, HKIV Peptide, HXKP Peptide, LGLK Peptide, MODY2 Peptide, Gk Peptide, Gls006 Peptide, GCK Peptide, BA4487 Peptide, glk Peptide, hk4 Peptide, hhf3 Peptide, hkiv Peptide, hxkp Peptide, gck-A Peptide, mody2 Peptide, glucokinase Peptide, GLUKA Peptide, RNGK2 Peptide, glucokinase Peptide, glucokinase (hexokinase 4) L homeolog Peptide, glucokinase (hexokinase 4) Peptide, GCK Peptide, Gck Peptide, glcK Peptide, Bphyt_1025 Peptide, Halhy_6548 Peptide, gk Peptide, gck.L Peptide, gck Peptide
    Sujet
    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
    Poids moléculaire
    51 kDa
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