A synthetic peptide for use as a blocking control in assays to test for specificity of HIST1 H1 E antibody, Alternative Names: HIST1H2AE control peptide, HIST1H2AE antibody Blocking Peptide, Anti-HIST1H2AE Blocking Peptide, histone cluster 1, H2ae Blocking Peptide, H2A.1 Blocking Peptide, H2A.2 Blocking Peptide, H2A/a Blocking Peptide, H2AFA Blocking Peptide, HIST1H2AB Blocking Peptide, HIST1H2AE, HISTH2AE-1, HISTH2AE 1, HISTH2AE-1 Blocking Peptide, HISTH2AE 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
HIST1H2AE
(Histone Cluster 1, H2ae (HIST1H2AE))
Synonymes
H2A.1 Peptide, H2A.2 Peptide, H2A/a Peptide, H2AFA Peptide, histone cluster 1 H2A family member e Peptide, HIST1H2AE Peptide
Sujet
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.