A synthetic peptide for use as a blocking control in assays to test for specificity of PABPC4 antibody, Alternative Names: PABPC4 control peptide, PABPC4 antibody Blocking Peptide, Anti-PABPC4 Blocking Peptide, Poly A binding protein 4 Blocking Peptide, PABPC4, PABPC-4, PABPC 4, PABPC-4 Blocking Peptide, PABPC 4 Blocking Peptide
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells.