Ribonucleotide Reductase M1 (RRM1) Peptide
RRM1
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN936944
Aperçu rapide pour Ribonucleotide Reductase M1 (RRM1) Peptide (ABIN936944)
Antigène
RRM1
(Ribonucleotide Reductase M1 (RRM1))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- ATGSYIAGTN GNSNGLVPML RVYNNTARYV DQGGNKRPGA FAIYLEPWHL
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of RRM1 antibody,
Alternative Names: RRM1 control peptide, RRM1 antibody Blocking Peptide, Anti-RRM1 Blocking Peptide, Ribonucleotide Reductase M1 Polypeptide Blocking Peptide, R1 Blocking Peptide, RIR1 Blocking Peptide, RR1 Blocking Peptide, RRM1, RRM-1, RRM 1, RRM-1 Blocking Peptide, RRM 1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- RRM1 (Ribonucleotide Reductase M1 (RRM1))
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Sujet
- RRM1 is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. Its gene is located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. Its gene may play a role in malignancies and disease that involve this region.
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Poids moléculaire
- 90 kDa
Antigène
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