Signal Transducer and Activator of Transcription 5B (STAT5B) Peptide
Aperçu rapide pour Signal Transducer and Activator of Transcription 5B (STAT5B) Peptide (ABIN937008)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- AVWIQAQQLQ GEALHQMQAL YGQHFPIEVR HYLSQWIESQ AWDSVDLDNP
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of STAT5 B antibody,
Alternative Names: STAT5B control peptide, STAT5B antibody Blocking Peptide, Anti-STAT5B Blocking Peptide, signal transducer and activator of transcription 5B Blocking Peptide, STAT5 Blocking Peptide, STAT5B, STATB-5, STATB 5, STATB-5 Blocking Peptide, STATB 5 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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Sujet
- The protein is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
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Poids moléculaire
- 90 kDa
Antigène
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