Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) Peptide
SIGLEC10
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937100
Aperçu rapide pour Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10) Peptide (ABIN937100)
Antigène
SIGLEC10
(Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- CHVDFSRKGV SAQRTVRLRV AYAPRDLVIS ISRDNTPALE PQPQGNVPYL
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of SIGLEC10 antibody,
Alternative Names: SIGLEC10 control peptide, SIGLEC10 antibody Blocking Peptide, Anti-SIGLEC10 Blocking Peptide, Sialic Acid Binding Ig-Like Lectin 10 Blocking Peptide, MGC126774 Blocking Peptide, PRO940 Blocking Peptide, SIGLEC-10 Blocking Peptide, SLG2 Blocking Peptide, SIGLEC10, SIGLEC-10, SIGLEC 10, SIGLEC-10 Blocking Peptide, SIGLEC 10 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
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Sujet
- SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
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Poids moléculaire
- 76 kDa
Antigène
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