A synthetic peptide for use as a blocking control in assays to test for specificity of DMAP1 antibody, Alternative Names: DMAP1 control peptide, DMAP1 antibody Blocking Peptide, Anti-DMAP1 Blocking Peptide, DNA methyltransferase 1 associated protein 1 Blocking Peptide, DMAP1, DMAP-1, DMAP 1, DMAP-1 Blocking Peptide, DMAP 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
DMAP1
(DNA Methyltransferase 1-Associated Protein 1 (DMAP1))
Sujet
DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication.