A synthetic peptide for use as a blocking control in assays to test for specificity of CA4 antibody, Alternative Names: Carbonic Anhydrase IV control peptide, Carbonic Anhydrase IV antibody Blocking Peptide, Anti-Carbonic Anhydrase IV Blocking Peptide, CA4 Blocking Peptide, CAIV Blocking Peptide, RP17 Blocking Peptide, Car4 antobody
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
CA4
(Carbonic Anhydrase IV (CA4))
Sujet
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IV is a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary capillaries and of proximal renal tubules. Its exact function is not known, however, it may have a role in inherited renal abnormalities of bicarbonate transport.