Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) Peptide
Aperçu rapide pour Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1) Peptide (ABIN937339)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- DGILEIPKGE LNGFYALQIN SLVDVSQPAY SQIQKLRGKN TTNDLVTAEA
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of RMI1 antibody,
Alternative Names: RMI1 control peptide, RMI1 antibody Blocking Peptide, Anti-RMI1 Blocking Peptide, Rmi1 Recq Mediated Genome Instability 1 Homolog Blocking Peptide, BLAP75 Blocking Peptide, C9orf76 Blocking Peptide, FLJ12888 Blocking Peptide, RP.1 Blocking Peptide, RMI1, RMI-1, RMI 1, RMI-1 Blocking Peptide, RMI 1 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- RMI1 (Homolog of Yeast RecQ-mediated Genome Instability 1 (RMI1))
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Sujet
- RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.
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Poids moléculaire
- 70 kDa
Antigène
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