Erythropoietin Receptor (EPOR) Peptide
EPOR
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937364
Aperçu rapide pour Erythropoietin Receptor (EPOR) Peptide (ABIN937364)
Antigène
EPOR
(Erythropoietin Receptor (EPOR))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- DHLGASLWPQ VGSLCLLLAG AAWAPPPNLP DPKFESKAAL LAARGPEELL
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of EPOR antibody,
Alternative Names: EPOr control peptide, EPOr antibody Blocking Peptide, Anti-EPOr Blocking Peptide, Erythropoietin Receptor Blocking Peptide, MGC138358 Blocking Peptide -
Purification
- Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- EPOR (Erythropoietin Receptor (EPOR))
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Sujet
- The erythropoietin receptor is a member of the cytokine receptor family. Upon erythropoietin binding, the erythropoietin receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis.
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Poids moléculaire
- 53 kDa
Antigène
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