TRAF Family Member-Associated NFKB Activator (TANK) Peptide
Aperçu rapide pour TRAF Family Member-Associated NFKB Activator (TANK) Peptide (ABIN937413)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- DKNIGEQLNK AYEAFRQACM DRDSAVKELQ QKTENYEQRI REQQEQLSLQ
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of TANK antibody,
Alternative Names: TANK control peptide, TANK antibody Blocking Peptide, Anti-TANK Blocking Peptide, TRAF family member-associated NFKB activator Blocking Peptide, I-TRAF Blocking Peptide, TRAF2 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- TANK (TRAF Family Member-Associated NFKB Activator (TANK))
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Sujet
- The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. TANK is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, TANK can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation.The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily.
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Poids moléculaire
- 48 kDa
Antigène
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