Amyloid beta (A4) Precursor Protein (APP) Peptide
APP
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937505
Aperçu rapide pour Amyloid beta (A4) Precursor Protein (APP) Peptide (ABIN937505)
Antigène
APP
(Amyloid beta (A4) Precursor Protein (APP))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- DPVKLPTTAA STPDAVDKYL ETPGDENEHA HFQKAKERLE AKHRERMSQV
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of APP antibody,
Alternative Names: APP control peptide, APP antibody Blocking Peptide, Anti-APP Blocking Peptide, Amyloid Precursor Protein Blocking Peptide, AAA Blocking Peptide, ABETA Blocking Peptide, ABPP Blocking Peptide, AD1 Blocking Peptide, APPI Blocking Peptide, CTFgamma Blocking Peptide, CVAP Blocking Peptide, PN2 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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Sujet
- APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
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Poids moléculaire
- 85 kDa
Antigène
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