A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN3 antibody, Alternative Names: KCNN3 control peptide, KCNN3 antibody Blocking Peptide, Anti-KCNN3 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 Blocking Peptide, KCNN3, KCNN-3, KCNN 3, KCNN-3 Blocking Peptide, KCNN 3 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
KCNN3
(Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
Synonymes
KCa2.3 Peptide, SK3 Peptide, SKCA3 Peptide, hSK3 Peptide, potassium calcium-activated channel subfamily N member 3 Peptide, potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 Peptide, Kcnn3 Peptide, KCNN3 Peptide
Sujet
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by KCNN3 is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP.