MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptide
MRE11A
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN937579
Aperçu rapide pour MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A) Peptide (ABIN937579)
Antigène
Mre11 (MRE11A)
(MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- DTFVTLDEIL RLAQENEVDF ILLGGDLFHE NKPSRKTLHT CLELLRKYCM
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of MRE11 A antibody,
Alternative Names: MRE11A control peptide, MRE11A antibody Blocking Peptide, Anti-MRE11A Blocking Peptide, MRE11 meiotic recombination 11 homolog A, S. cerevisiae Blocking Peptide, ATLD Blocking Peptide, HNGS1 Blocking Peptide, MRE11 Blocking Peptide, MRE11B Blocking Peptide, MRE11A, MREA-11, MREA 11, MREA-11 Blocking Peptide, MREA 11 Blocking Peptide -
Purification
- The antibody is affinity purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
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Sujet
- This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
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Poids moléculaire
- 80 kDa
Antigène
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