A synthetic peptide for use as a blocking control in assays to test for specificity of HLA-F antibody, Alternative Names: HLA-F control peptide, HLA-F antibody Blocking Peptide, Anti-HLA-F Blocking Peptide, Major Histocompatibility Complex Class I F Blocking Peptide, CDA12 Blocking Peptide, HLA-5.4 Blocking Peptide, HLA-CDA12 Blocking Peptide, HLAF Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
HLA-F (HLAF)
(HLA Class I alpha F (HLAF))
Sujet
HLA-F belongs to the HLA class I heavy chain paralogues. It is a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation.